PRODUCT MONOGRAPH. Pr. JEVTANA. ®. Cabazitaxel for injection. Concentrated Solution 40 mg/mL. (60 mg/ mL). Antineoplastic Agent. JEVTANA in combination with prednisone or prednisolone is indicated for the The printed package leaflet of the medicinal product must state the name and. Package leaflet: Information for the patient. JEVTANA® 60 mg concentrate and solvent for solution for infusion. cabazitaxel. Read all of this leaflet carefully.
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Antihistamine dexchlorpheniramine 5 mg or diphenhydramine 25 mg or equivalent antihistamine Corticosteroid dexamethasone 8 mg or equivalent steroid H 2 antagonist ranitidine 50 mg or equivalent H 2 antagonist Antiemetic prophylaxis is recommended and can be given orally or intravenously as needed. You will usually have an infusion once every 3 weeks. JEVTANA is contraindicated in patients who have a history of severe hypersensitivity reactions to cabazitaxel or to other drugs formulated with polysorbate Monitoring of complete blood counts is essential on a weekly basis during cycle 1 and before each treatment cycle thereafter so that the dose can be adjusted if needed.
Cabazitaxel (Jevtana) | – A Hematology Oncology Wiki
What is in this leaflet: Dosing and Dose Modifications. Men who are 65 years or older may be more likely to have these problems.
Company contact details Genzyme Therapeutics. Secondary prophylaxis with G-CSF should be considered in all patients at increased risk for neutropenia complications.
This includes medicines obtained without a prescription. Tell your HCP if you have blood in your urine, burning sensation during urination, or frequent or urgent need to urinate. Driving and using machines You packahe feel tired or dizzy when having this medicine. Uncommon may affect up to 1 in people: It belongs to a group of medicines called “taxanes” used to treat cancers. Your doctor will discuss these with you and will explain the potential risks and benefits cabazitxxel your treatment.
Find out more here. Talk to your HCP if you have concerns about fertility.
Jevtana – Patient Information Leaflet (PIL) – (eMC)
Febrile neutropenia or neutropenic infection. If this happens, do not drive or use any tools or machines until you feel better. Your HCP may prescribe treatment for you as needed.
To be taken into account if you are in a high risk group such as patients with liver disease, or epilepsy. Use a condom during sex if your partner is or could become pregnant. Obtain frequent blood counts to monitor for neutropenia. Low white blood cells, which can cause you to get serious infections, and may lead to death.
By reporting side effects you can help provide more information on the safety of this medicine.
Dosing and Dose Modifications
You are leaving www. Use G-CSF for secondary prophylaxis. Adverse Reactions Hematologic Lab Abnormalities. Possible side effects 5. Cabazitxael unused product or waste material should be disposed of in accordance with local requirements. Frequency not known cannot be estimated from the available data; interstitial lung disease inflammation of the lungs causing coughing and difficulty breathing. The product code s for this leaflet is: See a doctor immediately if you notice any of the following side effects: These packsge include the following:.
Do not take any new medicines without asking your HCP first. Contents of the pack and other information. You may feel tired or dizzy when packagr this medicine.
How much and how often to have The usual dose depends on your body surface area. Tell your doctor immediately if: