The key difference between maceration and percolation is that the maceration is the process of soaking or steeping something to make it soft. Various Methods of Extraction • Maceration • Percolation • Infusion • Decoction • Digestion; 9. Purposes of Extraction • The sole purpose of. Read 1 answer by scientists to the question asked by Mustafa Saddam on Dec 4,

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If the volume of solvent is reduced by evaporation then the extract may become concentrated, which may not be desired. During this period the drug swells up as the menstruum penetrates the cell walls. To recover the residual liquid pressure may be applied by a hydraulic press.

In this discussion we are concerned primarily with basic extraction procedures for crude drugs to obtain the therapeutically desirable portion and eliminate the inert crude material by treatment with a selective solvent, known as the menstruum.

After extraction the marc is not expressed.

At present no decoction is official in IP or BP. Macerated foods allow them to have a separate look making them much enjoyable and tasty on pairing them with desserts.

Maceration involves soaking or steeping.

It does not retain the menstruum and hence it is not necessary to press the macerztion. Multiple maceration – a process to prepare concentrated extract.

Both methods are extraction methods. Physical character of the drug: Maceration Percolation Digestion Infusion Decoction.

Difference Between Maceration and Percolation

The pot is filled with water and the perforated shelf is adjusted below the surface of water. Extra menstruum is not added to make up the required volume. Dilute preparations such as, tinctures may be prepared by maceration or by percolation but, concentrated preparations such as, liquid extracts or dry extracts should be prepared by percolation or reserved percolation process.


The pores are then occupied by air.

Difference Between Maceration and Percolation l Maceration vs Percolation

If the solvent is water maceration is generally adopted but, if the solvent is volatile then percolation process should be used. On the other hand, percolation involves filtration through a porous material. Maceration with adjustment – a process for tinctures made from unorganized drugs such as oleo-resins and gum resins. Later the water is filtered. After imbibition the moistened drug is evenly packed into the percolator. Multiple maceration process is carried out in the same way as simple maceration process, but the menstruum used is divided into two parts in double maceration process and three parts in triple maceration process.

The alternate filling and emptying of the body of the extractor goes on continuously till the drug is exhausted. Ques 5 What is reserved percolation? Once the solvent has penetrated into the cells solution of the constituents takes place and is governed by the solubility of the constituents in the solvent and again solubility depends on the temperature.

Furthermore, before cooking meat products, they macerate in a mixture of liquids for the purpose of marinating to make them better and enhance the taste.

Infusion, Decoction, Expression, Maceration, Percolation

Finally sufficient purified water is added to produce the required volume. Percolation makes use of gravity and biological techniques which allow some substances free of pollution.

Samanthi holds a B. Fresh infusion of Quassia. The marc is wrapped in cloth, is placed in the perforated inner vessel, which is enclosed in another vessel having an outlet for the expressed liquid.

Shaking of the drug during maceration is essential in order to replace the saturated layers around the drug with fresh menstruum. A fresh infusion is an aqueous solution of active constituents of a vegetable drug prepared by the process of infusion e. Dry extract – obtained by completely removing the solvent under reduced pressure. Maceration of Swedish Liqueur. Frequent agitation is required to reduce the localized concentration around the cells and tissues.


The process of maceration also helps in freeing the food from coming in contact with bacteria. Likewise, we can prepare different types of fruit dishes by macerating them.

The quantity of menstruum required for two macerations are calculated as follows:. Water is added and it is well stirred three or four times during the period of infusion. Furthermore, maceration does not involve gravity while percolation occurs towards the gravity. Maceration makes substances softer than before they were while percolation makes liquid drain through pores downwards.

Degree in Plant Science, M. The drug is allowed to stand for few days. After boiling, the liquid is cooled and filtered, more water is passed through the marc to produce the required volume.

Limitations of continuous hot percolation process: Sliced and bruised Coarse and moderately coarse powders Moderately fine powder. The selection of an extraction process mainly percooation on the physical nature of the drug. This process is a modified form of maceration where the drug is extracted by heating at a particular pressure.

If the physical character of the drug is such that it would block the soxhlet apparatus then this method is not suitable. Percolation is a widely used method used in the preparation of fluid extracts. The tinctures made by simple maceration process are.